Latest news from our suppliers.
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- Denovix
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- LGC Biosearch (Lucigen)
- Quantabio
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Quantabio | Continues to Set Standard in PCR Performance, Stability and Sustainability with New Line of Eco-friendly Lyophilized Products
New eQo 1-Step ToughMix kit features a warm-start reverse transcriptase in a single-tube master mix format that is conveniently shipped, stored and set up at room temperature BEVERLY, Mass.–(BUSINESS WIRE)–Quantabio, a leading provider of robust DNA and RNA amplification reagents for the most demanding molecular testing and life science research applications, today announced the launch […]
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Biotium | DNase pre-treatment of the EV exterior improves EV RNA yield
Extracellular vesicles (EVs) are known to contain RNA, including microRNA (miRNA) and mRNA, derived from the cell of origin. Studying EV RNA can be useful for many purposes: determining the cellular source of the EVs, for disease diagnostics (Ref. 1), and for identifying oncogenic RNAs (Ref. 2). Since EVs are very small (~30-200 nm in […]
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Biotium | ExoBrite™ CTB EV Stain assists in evaluating engineered EVs for targeted drug delivery against triple-negative breast cancer
Triple-negative breast cancer (TNBC) is an aggressive cancer type with no specific therapeutic targets, leaving chemotherapy as the primary treatment option. However, chemotherapy is often highly toxic for patients with limited effectiveness, underscoring the need for new therapeutic strategies. Researchers are examining the potential of extracellular vesicles (EVs)- small, cell-derived particles that are naturally highly […]
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Biotium | MitoView™ 633 offers advantages over TMRM as a probe for mitochondrial membrane potential
Mitochondria are essential for maintaining cellular health, with a key aspect of mitochondrial function being the mitochondrial membrane potential (mitochondrial potential). Mitochondrial potential is a valuable biomarker for detecting any disruptions linked to mitochondrial dysfunction. This is because it reflects the electrical gradient central to processes like ATP synthesis and calcium homeostasis across the inner […]
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Biotium | Bright and photostable CF® Dyes help validate fluorescence lifetime separation in multi-colour imaging
Fluorescence lifetime imaging microscopy (FLIM) has emerged as a powerful technique for multi-colour imaging, allowing researchers to distinguish fluorochromes beyond traditional spectral separation methods. By leveraging fluorescence lifetime differences, FLIM provides additional fluorochrome discrimination, enabling more complex imaging experiments with fewer spectral constraints. This approach is particularly valuable in confocal and Stimulated Emission Depletion (STED) […]
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Denovix | Comparing Hemocytometers and Automated Cell Counters
Written by Ben Capozzoli, DeNovix Application Scientist Since the invention of the hemocytometer counting chamber in 1874, biologists have been quantifying cells dispensed into the chamber of the slide through manual inspection under a microscope. These quantifications rely on knowing the exact volume in which you are counting. The following equation is used to translate […]
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Denovix | Is Erythrosin B a Better Choice than Trypan Blue for Cell Counting?
Written by Famatta Perry, PhD Cell counting is important for reproducible and accurate documentation of cell concentrations and viability, which can be used in a series of research, medical and biotechnological applications. Despite numerous documented issues with and limitations of Trypan Blue, it is still widely used in many research labs. This article aims to […]
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Denovix | Flow Cytometry and Image-Based Cell Counting: Complementary Technologies to Achieve Accurate Cell Quantifications and Characterizations
Written by Ben Capozzoli, DeNovix Application Scientist Understanding the number and characteristics of a given cell population is paramount to many cell/molecular biology studies. Many fields, like immunology, rely heavily upon the ability to quantify the number of cells in a population and the various characteristics those cells possess. Hemocytometers: A Traditional Cell Counting Method […]
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Denovix | How to Determine Cell Density of Microbial Cultures with OD600 Measurements and Factors
Written by Rachel Kennel, DeNovix Application Scientist The measurement of optical density (OD) at 600 nm is a common spectrophotometric method to determine the density of a bacterial or yeast culture, commonly during phases of bacterial or yeast growth. An OD600 measurement is a quick and convenient way to determine density for cells, which are […]
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Lucigen | Set up and walk away: same day targeted genotyping
Accelerate breeding programmes with high-speed, high-throughput NGS workflows Designing molecular breeding programmes to screen for desirable traits in plants and livestock can accelerate breeding cycles and enable precise genotype selection. But processing thousands of samples — with potentially complex genomes or difficult sample types — to deliver results within critical breeding windows is a major […]
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